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Orexin peptide levels of three brain regions in rats treated with saline (SAL) or clomipramine (CLI). (A) Orexin A levels in the hypothalamus (Hypo), hippocampus (Hipp) and frontal cortex (Front C). No significant difference between treatments groups was seen in any of these brain regions. (B) Orexin B levels in the same brain regions. Hypothalamic orexin B was significantly (t = 2.391, P = 0.021) decreased after three doses of treatment with CLI.
