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. Author manuscript; available in PMC: 2013 Feb 5.
Published in final edited form as: Am J Physiol Regul Integr Comp Physiol. 2003 Apr;284(4):R1098–R1107. doi: 10.1152/ajpregu.00165.2002

Table 2.

Effect of 20% VE on MAP, HR, MRAP, and RSNA after intravenous losartan in rats receiving chronic infusions

Vehicle-Infused Rats
 ANG II-Infused Rats
Baseline 20% VE Baseline 20% VE
MAP mmHg 88.5 ± 4 94 ± 4 89.7 ± 5 92 ± 5
HR, beats/min 342 ± 11 316 ± 12 372 ± 16 355 ± 15
MRAP, mmHg − 1.23 ± 0.23 − 0.19 ± 0.2* −0.81 ± 0.3 0.51 ± 0.3*
ΔMRAP, mmHg 0.9 ± 0.07 1.1 ± 0.2
RSNA, % 100 74 ± 3* 100 79 ± 2*

Values are means ± SE; n = 12 in both groups.

*

P < 0.05 vs. baseline.