Figure 2.

β-AR blockade in BLA has no effect on CPP memory retrieval. A, Coronal drawings (bregma, −2.76 mm) showing injector tip placements for BLA infusions. BLA infusions (arrows) of (B) propranolol before a second CPP trial or (C) nadolol before a first CPP trial, but not saline, had no effect on CPP expression during the infusion trial, but prevented CPP expression during subsequent infusion-free trials. BLA infusions of (D) propranolol or (E) nadolol had no effect on locomotor activity, as measured by photobeam breaks, when administered before a CPP trial. ***p < 0.001, **p < 0.01, and *p < 0.05. Error bars indicate SEM.