Table 1. Mammalian and yeast ubiquitin conjugating enzymes and interacting ubiquitin ligases involved in ER dislocation.

UBC (ubiquitin conjugating domain); UBA (ubiquitin-associated domain). The ER membrane is represented by a shaded bar with the ER lumen in the upper right corner.

Mammalian ubiquitin conjugating enzymes	Topology/Functional Domains	Interacting mammalian ubiquitin ligases
UBE2J1 (UBC6E, NCUBE1) [65]		HRD1 [45] RMA1 [22]
UBE2J2 (UBC6, NCUBE2) [65]		Parkin [66]
UBE2G2 (UBC7) [65]		Gp78 [65] HRD1 [67] Parkin [65]
Yeast ubiquitin conjugating enzymes		Interacting yeast ubiquitin ligases
Ubc1 [65]		Hrd1p [65]
Ubc6 [65]		Doa10 [65]
Ubc7 [65]		Hrd1p [65] Doa10 [65]