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. Author manuscript; available in PMC: 2013 Feb 5.
Published in final edited form as: Trends Cell Biol. 2011 Nov 3;22(1):22–32. doi: 10.1016/j.tcb.2011.09.010

Table 3. p97 co-factors involved in mammalian dislocation.

Protein Function Interaction Domain
UFD1/NPL4 [12] Facilitates engagement of poly-ubiquitin proteins UBX
UBXD2 (Erasin) [43] p97 recruitment UBX
UBXD8 [45] p97 recruitment UBX
YOD1 [13] De-ubiquitylating activity at p97 UBX
VIMP [42] Recruits p97 to the ER membrane Unknown
Peptide: N-glycosidase [100] Enzymatic removal of N-linked glycans PUB
Ataxin3 [15] De-ubiquitylating activity at p97 VCP binding motif (VBM)
SAKS1 [50] Mediates ubiquitin interactions UBX