Table 1.
Cases | Controls | ||||
---|---|---|---|---|---|
N1 | % | N1 | % | OR2 (95% CI) | |
Age | |||||
<50 | 2044 | 35.8 | 2238 | 35.0 | 1.0 (ref) |
50–59 | 1955 | 34.3 | 2304 | 36.1 | 0.92 (0.84 – 1.00) |
>59 | 1708 | 29.9 | 1847 | 28.9 | 1.00 (0.91 – 1.09) |
Race | |||||
Caucasian | 5512 | 96.6 | 6110 | 95.6 | 1.0 (ref) |
Not Caucasian | 163 | 2.9 | 242 | 3.8 | 0.75 (0.62 – 0.90) |
Education | |||||
≥ 12 years | 2566 | 45.1 | 2915 | 45.9 | 1.0 (ref) |
1–3 years college | 1496 | 26.3 | 1717 | 26.9 | 1.01 (0.93 – 1.11) |
College graduate | 1631 | 28.6 | 1742 | 27.3 | 1.12 (1.03 – 1.23) |
Body mass index (kg/m2) | |||||
Premenopausal | |||||
<24 | 1102 | 46.8 | 1131 | 43.9 | 1.0 (ref) |
24–27 | 669 | 28.4 | 737 | 28.6 | 0.94 (0.81 – 1.07) |
>27 | 584 | 24.8 | 707 | 27.5 | 0.82 (0.71 – 0.95) |
Postmenopausal | |||||
<24 | 973 | 31.5 | 1158 | 33.2 | 1.0 (ref) |
24–27 | 1044 | 33.8 | 1142 | 32.7 | 1.07 (0.95 – 1.21) |
>27 | 1069 | 34.6 | 1192 | 34.1 | 1.04 (0.92 – 1.17) |
Age at menarche | |||||
<12 | 1227 | 21.5 | 1284 | 20.1 | 1.0 (ref) |
12–14 | 3827 | 67.1 | 4261 | 66.7 | 0.93 (0.85 – 1.02) |
>14 | 595 | 10.4 | 785 | 12.3 | 0.78 (0.67 – 0.89) |
Parity | |||||
Nulliparous | 812 | 14.2 | 769 | 12.0 | 1.0 (ref) |
1–2 | 2508 | 43.9 | 2567 | 40.2 | 0.92 (0.82 – 1.03) |
>2 | 2381 | 41.7 | 3047 | 47.7 | 0.69 (0.61 – 0.77) |
Menopausal status | |||||
Premenopausal | 2363 | 43.2 | 2594 | 42.0 | 1.0 (ref) |
Postmenopausal | 3110 | 56.8 | 3516 | 57.5 | 0.87 ( 0.77 – 0.97) |
Family history of breast cancer | |||||
No | 4525 | 79.2 | 5536 | 86.7 | 1.0 (ref) |
Yes | 1150 | 20.1 | 817 | 12.8 | 1.58 (1.41 – 1.78) |
History of benign breast disease | |||||
No | 3899 | 68.3 | 4885 | 76.5 | 1.0 (ref) |
Yes | 1752 | 30.7 | 1445 | 22.6 | 1.10 (1.06 – 1.15) |
Recent alcohol consumption (drinks/week) | |||||
0 | 983 | 17.2 | 1119 | 17.5 | 1.0 (ref) |
<2 | 2526 | 44.3 | 3012 | 47.2 | 0.95 (0.86 – 1.05) |
2 – <4 | 786 | 13.8 | 862 | 13.5 | 1.04 (0.91 – 1.18) |
4+ | 1407 | 24.7 | 1391 | 21.8 | 1.18 (1.05 – 1.32) |
Smoking | |||||
Never smokers | 2667 | 46.8 | 2945 | 46.3 | 1.0 (ref) |
Ever smokers | 3034 | 53.2 | 3437 | 53.8 | 1.00 (0.93 – 1.08) |
Multivitamin use | |||||
No | 3166 | 56.9 | 3462 | 55.5 | 1.0 (ref) |
Yes | 2403 | 43.1 | 2782 | 44.5 | 0.94 (0.87 – 1.01) |
Column totals are unequal due to missing data
Odds ratios are adjusted for age and state of residence