Table 1.
WT | Kit W/W-v | ANOVA (P<) | |||||
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Intact | Ovx | Intact | Ovx | Genotype | Surgery | Interaction | |
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Total Tibia | |||||||
Bone length (mm) | 17.56 ± 0.10 | 17.96 ± 0.04 | 17.31 ± 0.12 | 17.73 ± 0.08 | 0.003 | 0.001 | NS |
Bone volume (mm3) | 16.35 ± 0.24 | 14.82 ± 0.23 | 13.99 ± 0.39 | 12.93 ± 0.34 | 0.001 | 0.001 | NS |
Tibial Diaphysis (cortical bone) | |||||||
Tissue volume (mm3) | 0.181 ± 0.002 | 0.177 ± 0.002 | 0.162 ± 0.002 | 0.159 ± 0.002 | 0.001 | NS | NS |
Cortical volume (mm3) | 0.137 ± 0.002 | 0.128 ± 0.002 | 0.123 ± 0.002 | 0.119 ± 0.002 | 0.001 | 0.001 | NS |
Marrow volume (mm3) | 0.044 ± 0.001 | 0.048 ± 0.001 | 0.039 ± 0.001 | 0.041 ± 0.002 | 0.001 | 0.03 | NS |
Cortical thickness (μm) | 257 ± 4 | 238 ± 2 | 241 ± 2 | 231 ± 4 | 0.001 | 0.001 | NS |
Data are mean ± SE