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. 2012 Oct 4;2:14. doi: 10.1186/2045-3329-2-14

Table 1.

Adult sarcoma study descriptions

Location & time Author NCases NControls/Cohort Risk cactors examined
Cohort Studies UK & France 1942–1986 [5,6]
Le vu et al. (1998), Menu-Branthomme et al. (2004)
OS 32, STS 25
4,400, 4,400
Radiotherapy
Finland 1953–2000 [7]
Virtanen et al. (2006)
STS & MBT 147
295,712
Radiotherapy
France 1954–1983 [8]
Rubino et al. (2005)
STS & MBT 14
6,597
Radiotherapy
Japan 1958–2001 [9]
Samartzis et al. (2011)
MBT 19
120,321
Ionizing radiation- atomic bomb
USA 1973–1995 [10]
Hwang et al. (2003)
STS 135
194,798
Radiotherapy
Amsterdam 1984–1996 [11]
Renwick et al. (1998)
KS 99
3,443
HHV8 infection
Nested Case–control UK 1940–1983 [12]
Hawkins et al. (1996)
MBT 59
220
Radiotherapy
International-multiple locations ?-1991 [13]
Kogevinas et al. (1995)
STS 11
55
Phenoxy herbicides, chlorophenols, dioxins
Case–control England & Wales 1968–1976 [14]
Balarajan et al. (1984)
STS 1,961
1,961
Agriculture and forestry occupations
Sweden 1975–1982 [15]
Wingren et al. (1990)
STS 96
650
Job type, chemical agents, and other occupational factors
Kansas, USA 1976–1982 [16,17]
Hoar et al. (1986), Zahm et al. (1989)
STS 228, STS 133
1610, 948
Agricultural herbicide use, tobacco use, medical history, occupation
Umea, Sweden 1978–1983 [18]
Hardell et al. (1988)
STS 54
311
Phenoxyacetic acids, chlorophenols
Uppsala, Sweden 1978–1986 [19]
Eriksson et al. (1990)
STS 237
237
Occupation, occupational exposures, dioxins
Wisconsin, USA 1979–1989 [20]
Moss et al. (1995)
OS 167
989
Fluoridated drinking water
Wisconsin, USA 1980–1997 [21]
Guse et al. (2002)
OS 319
3,198
Radium in drinking water
Washington, USA 1981–1984 [22]
Woods et al. (1987)
STS 128
694
Phenoxy herbicides, chlorophenols, and other occupational exposures
Victoria, Australia 1982–1988 [23]
Smith et al. (1992)
STS 30
60
Phenoxy herbicides and chlorophenols
New York & Washington DC, USA 1982-? [24]
Engels et al. (2003)
KS 29
57
Immunologic and virologic factors
Northern Italy 1983–1998 [25]
Fioretti et al. (2000)
STS 104
505
Menstrual and reproductive factors
USA-multiple locations 1984–1988 [26,27]
Hoppin et al. (1998), Hoppin et al. (1999)
STS 295, STS 200 & MBT 51
1908, 1908
Chlorophenols and other occupational exposures
USA-multiple locations 1984-? [28]
Moore et al. (1996)
KS 21
42
Kaposi's sarcoma-associated herpesvirus infection
Northeast Italy 1985–1991 [29-31]
Franceschi et al. (1992), Serraino et al. (1992), Serraino et al. (1991)
STS 93, STS 93, STS 88
721, 721, 610
Occupational factors, tobacco, alcohol, drugs, pesticides, and history of infection
Manua, Italy 1989–1998 [32]
Comba et al. (2003)
STS 37
171
Residence near industrial waste incinerators
Uganda 1994–1998 [33]
Ziegler et al. (2003)
KS 117
1,282
HHV8 infection
Europe-multiple locations 1995–1997 [34]
Merletti et al. (2006)
MBT 96
2,632
Job type and occupational exposures
Sicily, Naples, and Rome 1998–2001 [35]
Goedert et al. (2002)
KS 141
192
Birth order, sexual history, medical history, and cigarette consumption
Ecologic France 1980–1995 [36]
Viel et al. (2000)
STS 110
N/A
Residence near industrial waste incinerators
Case-series USA-multiple locations 1960–1992 [37]
Cope et al. (2000)
ES 306
N/A
Hernias
Bologna, Italy 1981–2001 [38] Longhi et al. (2005) OS 962 N/A Height, stature, and growth rate

STS = Soft tissue sarcoma, MBT = Malignant bone tumor, KS = Kaposi's sarcoma, OS = Osteosarcoma, ES = Ewing's sarcoma, CS = Chondrosarcoma.

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