Table 1. Characteristics of included studies potentially suitable for meta-analysis (universal health care systems).
Paper | Country of Study | Data Source (s) | Population Included | Years of Diagnosis | Measure of SEP | No. of SEP groups | Treatment given within | Age Range | Confounders Controlled For: | Quality Score | ||||
Age | Sex | Stage | Histology | Other | ||||||||||
Berglund et al, 2010 [19] | Sweden | Regional Lung Cancer Register (RLCR) - Sweden, Cause of Death Register and LISA (insurance and demographics) | Uppsala/Orebro region in central Sweden | 1996–2004 | Education levela | 3 | NR | 30+ | Yes | Yes | Yes | Yes | Performance status, year of diagnosis, smoking status | 6 |
Berglund et al, 2012 [22] | England | Thames Cancer Registry, HES, LUCADA | South-east England | 2006–2008 | IMD 2007 income domain | 5 | NR | 0–80+ | Yes | Yes | Yes | Yes | Co-morbidity | 6 |
Campbell et al, 2002 [35] | Scotland | Scottish Cancer Registry and hospital case notes | Random sample from North/NE Scotland (with hospital record) | 1995–1996 | Carstairs Index | 5 | 12 months | NR | Yes | Yes | Yes | Yes | Health board, distance to cancer centre, mode of admission | 5 |
Crawford et al, 2009 [36] | England | Northern and Yorkshire Cancer Registry and Information Service (NYCRIS) | Northern and Yorkshire region | 1994–2002 | IMD 2004 (access to services domain removed) | 4 | 6 months | NR | Yes | Yes | No | Yes | Travel time (but overall results not stratified by travel time used here). Histology not included in receipt of any treatment analysis. | 4 |
Erridge et al, 2002 [37] | Scotland | Scottish Cancer Registry and medical records | Scotland (with hospital record) | 1995 | Carstairs Index | 5 | 6 months | <60– 80+ | Yes | Yes | Yes | Yes | Health board (not inc in receipt of radiotherapy), diagnosis by specialist, management by oncologist | 6 |
Erridge et al, 2009 [18] | Scotland/Canada | Scottish Cancer Registry and medical records; British Columbia Cancer Registry | Scotland/British Columbia | 1995 | Carstairs Index/average household income | 2 | 6 months | <60– 80+ | Yes | Yes | Yes | Yes | Travel time, CT scan | 4 |
Gregor et al, 2001 [38] | Scotland | Scottish Cancer Registry and medical records | Scotland (with hospital record) | 1995 | Carstairs Index | 5 | 6 months | <60–80+ | Yes | Yes | Yes | Yes | Referral to specialist within 6 months of diagnosis | 6 |
Jack et al, 2003 [39] | England | Thames Cancer Registry | South-east England | 1995–1999 | Townsend (median score per health authority) | Contin-uousb | NR | <35–85+ | Yes | Yes | Yes | Yes | First hospital visited is a radiotherapy centre, basis of diagnosis, incidence. Health authority/hospital used as 2nd level in multi-level model. | 4 |
Jack et al, 2006 [40] | England | Thames Cancer Registry and medical records | South-east London (with hospital record) | 1998 | IMD 2000 | 5 | 6 months | <55–85+ | Yes | Yes | Yes | Yes | Consultant specialty, basis of diagnosis (hospital, number of symptoms in some analyses) | 6 |
Jones et al,2008 [41] | England | Northern and Yorkshire Cancer Registry and Information Service (NYCRIS) | Northern and Yorkshire region | 1994–2002 | IMD 2004 (access to services domain removed) | Contin-uousc | NR | NR | Yes | Yes | No | Yes | Travel time to hospital | 4 |
Mahmud et al, 2003 [42] | Ireland | National Cancer Registry of Ireland (NCRI) | Republic of Ireland | 1994–1998 | SAHRU area-based material deprivation index | 3 | 6 months | 15–80+ | Yes | Yes | No | Yes | Health board, year of diagnosis | 4/2d |
McMahon et al, 2011 [43] | England | Eastern Cancer Registry and Information Centre (ECRIC) | East of England | 1995–2006 | IMD 2004 (access to services domain removed) | 5 | NR | <60–80+ | Yes | Yes | No | Yes | Year of diagnosis | 4 |
Pollock &Vickers, 1998 [44] | England | HES FCEs | North/South Thames (admitted to hospital) | 1992–1995 | Townsend | 10 | NR | <100 | Yes | Yes | No | No | Hospital, mode of admission | 3 |
Raine et al, 2010 [45] | England | HES FCEs | England (admitted to hospital) | 1999–2006 | IMD | 5 | NR | 50– 90+ | Yes | Yes | No | No | Trust, year of admission, mode of admission | 3 |
Riaz et al, 2012 [34] | England | NCIN/UKACR cancer registries | England | 2004–2006 | IMD 2004 | 5 | NR | 0– 85+ | Yes | Yes | No | No | Government Office Region | 4 |
Rich et al, 2011(1) [46] | England | LUCADA supplied by 157 NHS trusts | England | 2004–2007 | Townsend | 5 | NR | NR | Yes | Yes | Yes | Yes | Performance status. Adjusted for clustering by NHS trust | 5 |
Rich et al, 2011(2) [21] | England | LUCADA and HES | England | 2004–2008 | Townsend | 5 | NR | 30–100 | Yes | Yes | Yes | Yes | Co-morbidity, ethnicity, surgery centre, radiotherapy centre, trial entry. Adjusted for clustering by NHS trust | 5 |
Stevens et al, 2007 [23] | New Zealand | Regional hospital and oncology databases checked against NZ cancer registry | Auckland-Northland region patients managed in secondary care | 2004 | NZ Deprivation Index | 2 | NR | <60–80+ | Yes | Yes | Yes | Yes | Co-morbidity, private sector care, care discussed at MDM | 3 |
Stevens et al, 2008 [47] | New Zealand | Regional hospital and oncology databases checked against NZ cancer registry | Auckland-Northland region patients managed in secondary care | 2004 | NZ Deprivation Index | 10 | NR | <60–80+ | Yes | Yes | Yes | Yes | Co-morbidity, private sector care, ethnicity | 5 |
Quality score ranges from 1 (lowest quality) to 6 (highest quality).
Socioeconomic index (SEI) and household income also measured but individual education level used in analyses as it contained least missing data.
Odds ratio for 1 unit increase in deprivation score, range unknown.
Odds ratio for 1 unit increase in deprivation score, range 1–80.
Quality score 4 where adjusted OR used and 2 where unadjusted rates used.
HES, Hospital Episode Statistics; HES FCE, Hospital Episode Statistics Finished Consultant Episode; IMD, Index of Multiple Deprivation; LUCADA, Lung Cancer Audit; MDM, multi-disciplinary meeting; NCIN/UKACR, National Cancer Information Network/UK Association of Cancer Registries; NR, not reported; OR, odds ratio; SEP, socioeconomic position; UHCS, universal health care system.