Figure 2. Effect of tariquidar on the sensitivity of HEK/pcDNA and HEK/MRP7 cells to anticancer drugs.

HEK/pcDNA cells and HEK/MRP7 cells were cultured for 24 h before tariquidar was added. After 1 h incubation, paclitaxel (A), docetaxel (B), vincristine (C), vinorelbine (D), vinblastine (E), or cisplatin (F) was added, and the cultures were incubated for 72 h. Cell viability was measured by the MTT assay. Results were representative of 3 independent experiments.