Table 2. Distribution of Alleles and Genotypes of IL-23R Variants and Their Association with AML Risk.

	AML (n = 545)		Controls (n = 1146)		OR (95%CI)a	P a	OR (95%CI)b	P b
	N	%	N	%
rs1884444 T>G c
TT	223	41.5	519	45.7	1.00		1.00
TG	254	47.3	496	43.6	1.19(0.96, 1.48)	0.115	1.34(1.04, 1.72)	0.024
GG	60	11.2	122	10.7	1.15(0.81, 1.62)	0.445	1.05(0.70, 1.57)	0.814
TG/GG	314	58.5	618	54.3	1.18(0.96, 1.46)	0.113	1.28(1.01, 1.62)	0.047
G allele	34.8%		32.5%		1.11(0.95, 1.29)	0.189	1.12(0.94, 1.34)	0.214
rs6682925 T>C d
TT	184	35.0	452	40.5	1.00		1.00
TC	247	47.1	522	46.7	1.16(0.93, 1.46)	0.197	1.25(0.96, 1.62)	0.103
CC	94	17.9	143	12.8	1.62(1.18, 2.21)	0.003	1.48(1.03, 2.13)	0.033
TC/CC	341	65.0	665	59.5	1.26(1.02, 1.56)	0.036	1.30(1.01, 1.67)	0.039
C allele	41.4%		36.2%		1.25(1.07, 1.45)	0.004	1.22(1.03, 1.45)	0.022

^aCrude odds ratio (OR), 95% confidence interval (CI) and corresponding P value.

^bAdjusted for age and gender.

^cGenotypes were unavailable in 8 cases and 9 controls.

^dGenotypes were unavailable in 20 cases and 29 controls.