Table 3. Stratification Analysis of rs1884444 and rs6682925 Genotypes by Selected Variables in AML Patients and Controls.

Characteristics	rs1884444						rs6682925
	Case		Control		OR(95%CI)	P d	Case		Control		OR(95%CI)	P d
	TT	TG/GG	TT	TG/GG			TT	TC/CC	TT	TC/CC
gender
Male	115	172	365	448	1.30(0.95, 1.78)a	0.848	98	183	318	483	1.26(0.91, 1.74)a	0.745
Female	108	142	154	170	1.24(0.86, 1.80)a		86	158	134	182	1.37(0.93, 2.01)a
Age at diagnosis, year
≤45	134	159	48	67	0.85(0.55, 1.32)b	0.030	109	179	41	74	0.91(0.58, 1.43)b	0.062
>45	89	155	471	551	1.52(1.14, 2.04) b		75	162	411	591	1.53(1.13, 2.08)b
Lineage
Myeloid	158	215	519	618	1.21(0.93, 1.59)c	0.985	131	234	452	665	1.25(0.94, 1.65)c	0.890
Myeloid and Lymphoid	61	93	519	618	1.26(0.86, 1.83) c		49	101	452	665	1.32(0.89, 1.95)c
Myeloid and Monocytic	4	6	519	618	1.20(0.34, 4.30) c		4	6	452	665	0.96(0.27, 3.44)c
Karyotype
t(8;21)	22	26	519	618	0.94(0.51, 1.73) c	0.726	15	31	452	665	1.29(0.67, 2.48)c	0.740
t(15;17)	23	39	519	618	1.34(0.74, 2.42) c		21	42	452	665	1.26(0.69, 2.29)c
Complex	53	60	519	618	0.93(0.61, 1.40) c		44	63	452	665	0.91(0.59, 1.39)c
Others	8	11	519	618	1.05(0.41, 2.69) c		6	13	452	665	1.34(0.50, 3.63)c
Normal	95	136	519	618	1.27(0.92, 1.74) c		78	148	452	665	1.31(0.94, 1.82)c
Unknown	22	42					20	44			–
Molecular subtype
PML/RARα	26	50	519	618	1.55(0.90, 2.69) c	0.647	23	51	452	665	1.37(0.78, 2.43)c	0.922
AML1/ETO	25	29	519	618	0.94(0.53, 1.66) c		19	33	452	665	1.10(0.60, 2.01)c
Others	24	32	519	618	1.08(0.61, 1.91) c		21	34	452	665	1.06(0.59, 1.90)c
No common fusion gene ranscripts	126	170	519	618	1.17(0.88, 1.56) c		102	188	452	665	1.23(0.92, 1.66)c
Unknown	22	33					19	35

^aAdjusted for age.

^bAdjusted for gender.

^cAdjusted for age and gender.

^d P value for heterogeneity test based on χ²-based Q test.