Table 1.

Selection of putative SCD containing Tel1/Mec1 targets

Kinetochore
Bub1	Spindle assembly protein.
Cbf2	Essential kinetochore protein, component of the CBF3 multisubunit complex.
Cnn1	Kinetochore protein of unknown function.
Mad1	Spindle assembly protein.
Spc105	Subunit of a kinetochore-microtubule binding complex that bridges centromeric heterochromatin and kinetochore. Required for kinetochore binding of SAC proteins.
Tid3	Component of the evolutionarily conserved kinetochore-associated Ndc80 complex.
Mitotic spindle
Bub2	Mitotic exit network regulator.
Nud1	Component of the spindle pole body outer plaque, required for exit from mitosis.
Spc72	Binds spindle pole bodies and links them to microtubules.
Spc97	Interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque.
Spc110	Inner plaque spindle pole body (SPB) component.
Stu1	Component of the mitotic spindle that binds to interpolar microtubules.
Cytokinesis
Cdc3	Component of the septin ring of the mother-bud neck that is required for cytokinesis.
Cla4	Involved in septin ring assembly and cytokinesis.
Cts1	Required for cell separation after mitosis.
Dse4	Degrades cell wall from the daughter side causing daughter to separate from mother.
Egt2	Required for proper cell separation after cytokinesis.
Elm1	Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis.
Cell bud
Ace2	Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters.
Bud3	Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis.
Bud8	Protein involved in bud-site selection.
Num1	Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip.
She3	Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud.
Cortical Actin cytoskeleton
Akl1	Ser-Thr protein kinase involved in endocytosis and actin cytoskeleton organization.
Ark1	Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton.
Bni1	Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation.
Las17	Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments.
Ndl1	Regulates dynein targeting to microtubule plus ends.
Sda1	Required for actin cytoskeleton organization.