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. 1972 Sep;10(3):433–438. doi: 10.1128/jvi.10.3.433-438.1972

Fatty Chains of Different Lipid Classes of Semliki Forest Virus and Host Cell Membranes

Raili Laine 1, Maija-Liisa Kettunen 1, Carl G Gahmberg 1, Leevi Kääriäinen 1, Ossi Renkonen 1
PMCID: PMC356483  PMID: 4342051

Abstract

Semliki Forest virus was grown in BHK-21 cells. The major classes of phospho-and glycolipids of the virus were analyzed for the compositions of fatty acids, aldehydes, and sphingosine bases, and the major glycerophospholipids were analyzed for the relative proportions of alkenyl-acyl, alkyl-acyl, and diacyl forms. All viral lipid classes proved to be mixtures of several molecular species. Each class contained a characteristic mixture of fatty chains, which was different in all other classes. All viral lipid classes resembled their counterparts of the host plasma membrane and also those of the endoplasmic reticulum. The gangliosides of the virus and the plasma membrane proved to be similar even at the level of individual molecular species. The number of certain lipid molecules in an average virion was less than the number of the protein molecules.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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