Figure 3. The defect of B cell development in CD19-Cre⁺ PDK1 ^flox/flox mice is caused by B cell intrinsic defects.

Bone marrow cells of CD19-Cre⁺ PDK1^{+ /+} and CD19-Cre⁺ PDK1 ^flox/flox mice were transferred into unirradiated Rag1 deficient recipients. Six weeks after transfer, flow cytometric analyses of B cell surface markers were performed with bone marrow cells, spleen cells and lymph node cells from the recipient mice. This is representative of two independent experiments.