Figure 3. Human TAAR5 is selectively activated by TMA and DMEA.

Responses of hTAAR5 to 42 different amines or amine-like substances. The concentration of all tested substances was 100 µM. Responses were normalized to the response to forskolin (10 µM). Data are given as mean ± SEM of 2–10 independent experiments, each performed in duplicates. TMA and DMEA induced signals significantly differing from mock-transfected controls (***p<0.001; **p<0.01).