Figure 4. TMA and DMEA act as agonists at the hTAAR5 receptor in a concentration-dependent manner.

Human TAAR5 responses were normalized to the response to forskolin (10 µM). EC₅₀ = 116 µM (TMA) and EC₅₀ = 169 µM (DMEA). Detection threshold for TMA is 1 µM (*p<0.05) and for DMEA 30 µM (*p<0.05). Error bars represent SEM.