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Figure 7. Overlaid total ion chromatograms (TIC) of Lys-C peptide maps of non-reduced MAb-A Lot B, non-reduced Lot B Peak 1, and reduced Lot B Peak 1. H14(Ox.M252)-S-S-H18 is the disulfide linked heavy chain peptide containing oxidized methionine 252 (Ox. M252). H24-S-S-H28(Ox.M428) is the disulfide linked heavy chain peptide containing oxidized methionine 428 (Ox. M428). L6(clipped)-S-S-L12 is the disulfide linked light chain peptide containing a non-specific clip.
