Table 1. Characterization data for SEC-enriched IgG1 dimer and monomer samples.
Enriched IgG1 species | Approximate molar mass by SEC-MALLS (g/mol) |
% Purity of Enriched Fraction by SEC | % main peak from non-reduced CE-SDS | Potency by HUVEC |
---|---|---|---|---|
Dimer |
300 x 103 g/mol |
92% |
83% |
42 |
Monomer | 150 x 103 g/mol | 96% | 90% | 100 |