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. 2013 Feb 5;8(2):e56096. doi: 10.1371/journal.pone.0056096

Table 1. QTLs for glomerular injury score in postmenopausal F2 (Dahl S x R) intercross female rats.

QTL Model Rat-location LOD %
GIS-pm1 Recessive Chr4: 74–112 Mbp 3.54 (HS) 12 (↓)
GIS-pm2 Dominant Chr3: 80–120 Mbp 2.72 (S) 9 (↑)
GIS-pm3 Dominant Chr5: 125–145 Mbp 2.37 (S) 8 (↑)
GIS-pm4 Dominant Chr2: 215–235 Mbp 1.70 (Sug) 6 (↓)
GIS-pm5 Recessive Chr7: 15–35 Mbp 1.28 (Sug) 5 (↓)

QTL, quantitative trait locus; GIS, glomerular injury score; Chr, chromosome; % , the amount in % of total trait variance that would be explained by a QTL at these loci; Mbp, mega-base pair; LOD, logarithm of the odds score derived from the likelihood ratio statistic using a factor of 4.6; ↑, S-allele increases trait; ↓, S-allele decreases trait. Significance determined from 2000 permutations on data set: LOD 3.17 highly significant (HS); LOD 2.17 significant (S); LOD 1.15 suggestive (Sug).