Skip to main content
. 2012 Dec 7;13:117. doi: 10.1186/1471-2350-13-117

Table 2.

Genetic variants identified in the promoter regions of theIL2R alpha (CD25)gene locus

SNP (rs#) Position Polym orphism Flanking sequences Genotype Analysed individuals Allele Frequencya Frequencies (Hapmap YRI, CEU, CHB)b
rs12722617
−398
C>T
TTCGC[C/T] GCATC
CC
35
C
0.875
0.932, 1.000, NA
CT
5
T
0.125
0.068, 0.000, NA
ss410961577
−409
C>T
GGATC[C/T] TTCAG
CC
38
C
0.950
NA
CT
2
T
0.050
rs12722616
−516
C>T
AACAC [C/T] TTATA
CC
35
C
0.875
0.924, 1.000, 1.000
        CT 5 T 0.125 0.076, 0.000, 0.000

aFrequency corresponds for both allele and genotypes; b: YRI: Yoruba population representing Sub- Saharan African individual group, CEU: European, CHB: Han Chinese; NA: data not available.