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RBPs are extensively regulated by TFs and RBPs. (A) More TFs bind to RBP promoters than the promoters of other genes (B) RBPs bind to a greater proportion of RBP-encoding mRNAs. (C) RBP genes are more frequently spliced than other genes. *P < 0.05, **P < 0.005, relative to proteome, hypergeometric test (frequency data), Komologorov-Smirnov test (cumulative frequency data).
