Table 3. Summary of H3K4 di- and trimethylation patterns for genes that are not associated with methylated H3K4 in Δlae1 but are associated with methylated H3K4 in at least one other strain.
H3K4me2 | H3K4me3 | Regulation (Δlae1/lae1OE) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
WT | Δlae1 | lae1OE | WT | Δlae1 | lae1OE | Down/up | N/up | Down/down | N/down | Up/up |
+ | + | + | + | 1 | 7 | 1 | ||||
+ | + | + | 1 | 1 | 1 | 2 | ||||
+ | + | 2 | 5 | 5 | 9 | 1 | ||||
+ | + | + | 1 | |||||||
+ | 1 | 5 | 3 | |||||||
+ | + | 6 | 13 | 12 | 1 | |||||
+ | + | + | 1 | 1 | ||||||
+ | 2 | 2 | 11 | |||||||
+ | + | 1 | ||||||||
+ | 2 | 4 | 9 | 2 | ||||||
+ | 10 | 6 | 8 | 11 | ||||||
In total: | 4a | 26 | 44 | 46 | 27 |
+ indicates the presence of methylation in this strain, no symbol indicates absence; numbers specify the number of genes that show the respective pattern [up or down before the slash refers to regulation in Δlae1 vs. parent strain (WT), whereas right of the slash refers to regulation in the lae1OE vs. WT strain; N indicates no significant regulation (<twofold in either direction)]. WT, wild type.
lae1 not included.