Skip to main content
. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Parasite Immunol. 2013 Mar;35(3-4):109–119. doi: 10.1111/pim.12019

Figure 4. Blocking PS recognition enhances overall antigen presentation capacity of infected DCs.

Figure 4

(A, B) C57BL/6 WT and (C, D) FcR KO BMDCs were infected with lesion-derived amastigotes that were pre-treated with 9 μg/ml of mAb mch1N11 (PS-targeting) or isotype antibody in the presence or absence of different concentrations of OVA protein. After 24 h of infection, DCs were harvested and co-cultured with CFSE-labeled OTII CD4+ T cells for 3 days. The percentage of proliferating T cells was determined by CFSE dilution. (A, C) Graphs are representative of 3 independent experiments. (B, D) Graphs represent data from 3 pooled experiments. ** p <0.01, *** p <0.001.