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. Author manuscript; available in PMC: 2014 Feb 5.
Published in final edited form as: Anal Chem. 2013 Jan 17;85(3):1562–1570. doi: 10.1021/ac3027228

Figure 2.

Figure 2

BiP mRNA expression is upregulated in microchannel cell culture compared to 96-well cell culture under standard culture conditions. HEK and WT-hERG-HEK cells were cultured for 24 h, and G601S-hERG-HEK cells were cultured for 24 h or 48 h in media containing 10% FBS and 1 g/L glucose. Cells were seeded at a density of 630 cells/mm2. RT-qPCR analysis showed BiP mRNA expression was significantly higher in microchannels than 96-wells for all three cell lines. Results are the average ± standard error (SE); n=3 (wells) and n=3–4 (microchannels).