Table 3.
National Comprehensive Cancer Network (NCCN)–Armed Forces Institute of Pathology (AFIP) risk criteria after resection of primary gastrointestinal stromal tumors (GISTs), according to Miettinen and Lasota [9]
| Tumor parameters | Primary tumor location and risk of recurrence | ||||
|---|---|---|---|---|---|
| Size | Mitotic index | Stomach | Duodenum | Small intestine | Rectum |
| ≤2 cm | ≤5/50 HPFs | 0 % | 0 % | 0 % | 0 % |
| >2 cm, ≤5 cm | Very low (1.9 %) | Low (8.3 %) | Low (4.3 %) | Low (8.5 %) | |
| >5 cm, ≤10 cm | Low (3.6 %) | High (34 %) | Intermediate (24 %) | High (57 %) | |
| >10 cm | Intermediate (12 %) | High (52 %) | |||
| ≤2 cm | >5/50 HPFs | Insufficient data | Insufficient data | High (50 %) | High (52–71 %) |
| >2 cm, ≤5 cm | Intermediate (16 %) | High (50–86 %) | High (73–90 %) | ||
| >5 cm, ≤10 cm | High (55–86 %) | ||||
| >10 cm | |||||
HPFs high-powered fields