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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2012 Dec 5;22(2):251–260. doi: 10.1158/1055-9965.EPI-12-1007-T

Figure 1. Association of SNP on chromosome 5p15.33 and 6p22.1-p21.31 with lung cancer.

Figure 1

(A) Association of 111 directly genotyped SNPs (black) and 305 imputed SNPs (gray) with lung cancer, adjusted for sex, age, study site, % sub-Saharan African ancestry, % European ancestry, and number of pack-years smoked. Triangles denote SNPs which are associated with lung cancer in the NHGRI catalog. (B) Genes in the analyzed region and patterns of LD. Darker shading indicates higher r2 values and greater correlation between the SNPs. (C) Association of 320 directly genotyped SNPs (black) and 36,242 imputed SNPs (gray) with lung cancer, adjusted for sex, age, study site, % sub-Saharan African ancestry, % European ancestry, and number of pack-years smoked. Triangles denote SNPs which are associated with lung cancer in the NHGRI catalog. (D) Patterns of LD in the analyzed region. Darker shading indicates higher r2 values and greater correlation between the SNPs.