(A) Association of 242 directly genotyped SNPs (black) and 1,013 imputed SNPs (gray) with lung cancer, adjusted for sex, age, study site, % sub-Saharan African acnestry, % European ancestry, and number of pack-years smoked. Triangles denote SNPs which are associated with lung cancer the NHGRI catalog. (B) Patterns of LD in the analyzed region. Darker shading indicates higher r2 values and greater correlation between the SNPs.