Table 2.
Baseline and 1-Year Microarchitectural and Microstructural Finite Element Analysis Parameters (Mean ± SE)
| Baseline | 1 Year | P Value | |
|---|---|---|---|
| Radius | |||
| Radius Ct area, mm2 | 57.3 ± 2.5 | 56.0 ± 2.7 | .05 |
| Radius Tb area, mm2 | 179.6 ± 12.4 | 180.3 ± 12.5 | .15 |
| Radius Total area, mm2 | 236.8 ± 11.6 | 236.3 ± 11.5 | .04 |
| Radius Ct density, mg HA/cm3 | 915.0 ± 14.9 | 907.4 ± 17.2 | .12 |
| Radius Ct thickness, μm | 890 ± 50 | 878 ± 50 | .14 |
| Radius Tb density, mg HA/cm3 | 147.3 ± 8.5 | 147.9 ± 8.1 | .51 |
| Radius Tb number, 1/mm | 1.90 ± 0.07 | 1.92 ± 0.06 | .73 |
| Radius total density, mg HA/cm3 | 352.0 ± 16.2 | 348.6 ± 17.1 | .18 |
| Radius Tb bone stiffness, kN/mm | 14.9 ± 2.7 | 16.1 ± 2.6 | .67 |
| Radius whole bone stiffness, kN/mm | 87.7 ± 0.8 | 88.3 ± 4.5 | .65 |
| Radius cortical load share distal | 51 ± 2 | 41 ± 8 | .23 |
| Radius cortical load share proximal | 91 ± 2 | 91 ± 2 | .70 |
| Tibia | |||
| Tibia Ct area, mm2 | 124.7 ± 4.9 | 121.6 ± 5.1 | .005 |
| Tibia Tb area, mm2 | 589.7 ± 34.1 | 591.2 ± 34.0 | .052 |
| Tibia Total area, mm2 | 714.4 ± 31.7 | 712.7 ± 31.6 | .006 |
| Tibia Ct density, mg HA/cm3 | 875.2 ± 13.1 | 860.6 ± 14.9 | .002 |
| Tibia Ct thickness, μm | 1190 ± 60 | 1170 ± 60 | .02 |
| Tibia Tb density, mg HA/cm3 | 164.0 ± 6.6 | 164.3 ± 6.4 | .77 |
| Tibia Tb number, 1/mm | 1.98 ± 0.06 | 1.95 ± 0.07 | .62 |
| Tibia total density, mg HA/cm3 | 298.9 ± 12.7 | 294.9 ± 12.4 | .053 |
| Tibia Tb bone stiffness, kN/mm | 90.3 ± 6.0 | 95.0 ± 8.0 | .48 |
| Tibia whole bone stiffness, kN/mm | 262.9 ± 7.4 | 261.9 ± 8.5 | .51 |
| Tibia cortical load share distal, % | 39 ± 2 | 38 ± 2 | .18 |
| Tibia cortical load share proximal, % | 74 ± 2 | 73 ± 2 | .15 |
Abbreviations: Ct, cortical; TB, trabecular.
a
Values of P < .05 were considered significant and are shown in boldface.