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. Author manuscript; available in PMC: 2013 Feb 6.
Published in final edited form as: Semin Pediatr Neurol. 2009 Sep;16(3):120–126. doi: 10.1016/j.spen.2009.07.001

Figure 2. MRI findings typical of LIS1 mutations.

Figure 2

T2-weighted axial MRI image of a patient with classic lissencephaly is shown. There is almost complete agyria posteriorly, but some rudimentary gyri are seen anteriorly. This pattern of a more severely affected posterior cerebral cortex is typical of LIS1 mutations.