Table 1.
Effect of ultra-low-molecular-weight heparin (ULMWH) on energy metabolism and neural apoptosis in brain of rats after reperfusion for 24 h.
| Group | Dose (mg/kg) | Lactic acid (mmol/g) | ATPase (μmolPi/mg·h) | Percentage of cell apoptosis (%) |
|---|---|---|---|---|
| Sham | Saline | 0.75 ± 0.19 ** | 3.97 ± 0.60 ** | 5.6 ± 2.10 ** |
| Model | Saline | 1.06 ± 0.18 | 2.42 ± 0.67 | 20.3 ± 7.95 |
| ULMWH | 0.5 | 0.89 ± 0.13 * | 3.33 ± 0.57 * | 11.4 ± 3.70 * |
| ULMWH | 1 | 0.83 ± 0.09 ** | 3.49 ± 0.35 ** | 6.9 ± 2.32 ** |
| LMWH | 1 | 0.85 ± 0.13 * | 3.56 ± 0.57 ** | 10.6 ± 1.77 * |
Data are expressed as mean ± SD. (n = 9). Significance was determined by ANOVA, followed by Dunnett’s test. Asterisks represent a significant difference between model control group and other groups (*p < 0.05, **p < 0.01).