Table 2.
Mean overall Antibiotics Released and Release Rate Over Total 7-Days Period
| Group | Od (cm) | ID (cm) | Designed Thickness (cm) | Volume (cm3) | Surface area (cm2) | Total amount of antibiotics released (mg) | Initial antibiotics Release rate (mg/day) (Day 1 – Day 3) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BCT | BCTV | BCTV 0.5 | BCT | BCTV | BCTV 0.5 | ||||||
| A | 2.54 | 0.00 | 1.00 | 5.07 | 18.11 | 2.43 | 13.86 | 4.03 | 0.82 | 1.92 | 1.15 |
| B | 2.54 | 1.75 | 1.00 | 2.66 | 13.30 | 1.98 | 7.77 | 2.91 | 0.64 | 1.94 | 0.65 |
| C | 2.54 | 2.06 | 1.54 | 2.67 | 15.76 | 1.85 | 8.27 | 3.13 | 0.64 | 2.00 | 0.60 |
| D | 2.54 | 2.06 | 2.07 | 3.59 | 19.99 | 2.08 | 12.52 | 2.68 | 0.75 | 2.07 | 0.88 |
*
Note: BCT represents PMMA impregnated with 1.0g tobramycin;
BCTV represents PMMA impregnated with 1.0g tobramycin and 1.0g vancomycin;
BCTV 0.5 represents PMMA impregnated with 0.5g tobramycin and 0.5g vancomycin.