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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Gastroenterology. 2012 Feb 28;142(7):1483–92.e6. doi: 10.1053/j.gastro.2012.02.040

Figure 4.

Figure 4

CAD modulates Salmonella killing in a NOD2-dependent manner. (A) Gentamicin protection assay in HCT116 cells transfected with vector or CAD expression plasmid and MDP stimulated (10 µg/mL) during infection. Averages ±SD are shown. (B) Same as in A except cells were transfected with control or CAD short hairpin RNA plasmids 48 hours before infection. (C) Assay performed as in B except HCT116 cells were also transfected with either vector or NOD2 D291N expression construct (NOD2 DN). **P < .01, ***P < .001.