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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Mol Immunol. 2012 Jun 27;52(3-4):207–216. doi: 10.1016/j.molimm.2012.05.018

Fig. 2.

Fig. 2

Human but not mouse β2-GPI treatment alters IR-induced injury and PGE2 production in C57Bl/6 mice. C57Bl/6 mice were subjected to Sham or IR treatment in the presence or absence of β2-GPI purified from Balb/c (Balb B2), Rag-1−/− (Rag-1−/− B2) or Human (Human B2) plasma. Two hours after initiation of reperfusion, mid-jejunal intestinal sections (75–150 villi per animal) were scored (A) and ex vivo PGE2 (D) production were assessed. Representative H&E stained tissue sections (200×) are provided (B, C, E, F). PGE2 values are represented as pg/mg of intestinal protein. Each bar represents 4–10 animals. * = p ≤ 0.05 compared to Sham + peptide, φ = p ≤ 0.05 compared to I/R treatment animals not receiving peptides.