Table 3. Comparison of heavy-atom search methods.
| Search method | |||||||
|---|---|---|---|---|---|---|---|
| MR search procedure | SPHCLUSTER | SHELXD | |||||
| Resolution () | Total No. of HA clusters/single HA sites | Clusters located (MR run) | Sites found (MR run) | Sites added after LLG-map completion | Sites found after LLG-map completion | Solution found for single HA sites | |
| DR6HMT, MAD | 2.9 | 1/12 | 1 | 12 | 0 | 0 | |
| DR6HMT, SIRAS | 3.4 | 1/12 | 1 | 12 | 0 | 0 | |
| LysozymeTPT | 1.9 | 1/11 | 1 | 11 | 13 | 0 | Yes |
| 2.2 | 1 | 11 | 13 | 0 | Yes | ||
| LysozymeTaB | 1.8 | 2/12 | 2 | 12 | 0 | 12 | Yes |
| 2.8 | 2 | 12 | 0 | 12 | |||
| 3.8 | 1 | 6 | 6† | 12† | |||
| StyA1TaB | 2.4 | 2/12 | 1 | 6 | 6† | 12† | |
| MUAETaB | 3.3 | 3/18 | 3 | 12 | 0 | 0 | |
†
Visual inspection of LLG maps was required.