Skip to main content
. 2012 Dec 10;37(4):383–391. doi: 10.1111/apt.12180

Table 1.

Meta-analyses of prospective studies on interaction between NAT1 or NAT2 phenotypes respectively and meat intake in relation to risk of colorectal cancer

Low meat intake OR (95% CI) Medium meat intake OR (95% CI) High meat intake OR (95% CI) P-value
NAT 1*
 Slow acetylator 1 (ref) .92 (0.70–1.23) 1.02 (0.76–1.38)
 Fast acetylator .87 (0.66–1.14) .82 (0.63–1.07) .87 (0.66–1.15) .95
NAT 2
 Slow acetylator 1 (ref) .99 (0.77–1.29) .96 (0.74–1.24)
 Fast acetylator .92 (0.68–1.20) 1.00 (0.69–1.45) 1.25 (0.92–2.01) .07

The meta-analyses (Supplemental Table S3) were based on studies where information on the number of participants in each group was available.

*

NAT115,17

NAT2.12,15,17 Odds ratios (OR), 95% confidence interval (95% CI).

P-interaction. P-interactions were estimated by logistic regression analysis. Confidence intervals were obtained by bootstrapping.