Table 2.
Disease and therapy** | N | Average duration of follow-up, years
|
|||
---|---|---|---|---|---|
Duration on anti-TNF-α therapy | Duration on nonbiologic comparison | Duration on neither non-biologic comparison nor anti-TNF-α therapy | Total duration of follow-up (exit minus entry) | ||
RA | |||||
Initiated anti-TNF-α | 21,260 | 1.48 | 0.12 | 0.84 | 2.44 |
Did not switch | 18,177 | 1.49 | 0 | 0.75 | 2.24 |
Switched to non-biologic | 3,083 | 1.44 | 0.83 | 1.35 | 3.63 |
Did not initiate anti-TNF-α | 10,651 | 0 | 1.08 | 1.61 | 2.68 |
PsO, PsA, AS | |||||
Initiated anti-TNF-α | 4,368 | 1.21 | 0.18 | 0.65 | 2.04 |
Did not switch | 3,431 | 1.19 | 0 | 0.53 | 1.72 |
Switched to non-biologic | 937 | 1.27 | 0.80 | 1.13 | 3.20 |
Did not initiate anti-TNF-α | 5,836 | 0 | 0.97 | 1.61 | 2.58 |
IBD | |||||
Initiated anti-TNF-α | 3,329 | 0.96 | 0.24 | 1.23 | 2.43 |
Did not switch | 2,163 | 0.95 | 0 | 1.03 | 1.98 |
Switched to non-biologic | 1,166 | 0.97 | 0.68 | 1.63 | 3.28 |
Did not initiate anti-TNF-α | 6,078 | 0 | 1.07 | 1.44 | 2.51 |
Total*** | |||||
Initiated anti-TNF-α | 28,941 | 1.39 | 0.14 | 0.84 | 2.37 |
Did not switch | 23,877 | 1.40 | 0 | 0.14 | 2.14 |
Switched to non-biologic | 5,064 | 1,37 | 0.78 | 1.37 | 3.43 |
Did not initiate anti-TNF-α | 17,483 | 0.00 | 1.06 | 1.57 | 2.63 |
Restricted to patients with propensity scores in the overlapping region.
Patients with multiple autoimmune diseases are shown in multiple disease categories.
Under Total, each patient is shown in the table only once. The 5,064 patients contributing person-years to both the anti-TNF-α group and the non-biologic comparison group are shown with the anti-TNF-α group.