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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Pharmacoepidemiol Drug Saf. 2012 Oct 15;21(12):1311–1320. doi: 10.1002/pds.3354

Table 2.

Length of Treatment Episodes in Relation to Therapeutic Regimen, Years*

Disease and therapy** N Average duration of follow-up, years
Duration on anti-TNF-α therapy Duration on nonbiologic comparison Duration on neither non-biologic comparison nor anti-TNF-α therapy Total duration of follow-up (exit minus entry)
RA
 Initiated anti-TNF-α 21,260 1.48 0.12 0.84 2.44
  Did not switch 18,177 1.49 0 0.75 2.24
  Switched to non-biologic 3,083 1.44 0.83 1.35 3.63
 Did not initiate anti-TNF-α 10,651 0 1.08 1.61 2.68
PsO, PsA, AS
 Initiated anti-TNF-α 4,368 1.21 0.18 0.65 2.04
  Did not switch 3,431 1.19 0 0.53 1.72
  Switched to non-biologic 937 1.27 0.80 1.13 3.20
 Did not initiate anti-TNF-α 5,836 0 0.97 1.61 2.58
IBD
 Initiated anti-TNF-α 3,329 0.96 0.24 1.23 2.43
  Did not switch 2,163 0.95 0 1.03 1.98
  Switched to non-biologic 1,166 0.97 0.68 1.63 3.28
 Did not initiate anti-TNF-α 6,078 0 1.07 1.44 2.51
Total***
 Initiated anti-TNF-α 28,941 1.39 0.14 0.84 2.37
  Did not switch 23,877 1.40 0 0.14 2.14
  Switched to non-biologic 5,064 1,37 0.78 1.37 3.43
 Did not initiate anti-TNF-α 17,483 0.00 1.06 1.57 2.63
*

Restricted to patients with propensity scores in the overlapping region.

**

Patients with multiple autoimmune diseases are shown in multiple disease categories.

***

Under Total, each patient is shown in the table only once. The 5,064 patients contributing person-years to both the anti-TNF-α group and the non-biologic comparison group are shown with the anti-TNF-α group.