Table 3.

Outcomes during induction treatment

Outcomes	Placebo		Ciprofloxacin		Total		OR	95% CI	P-value
	n	%	n	%	n	%
Total patients	52	47.3	58	52.7	110	100
Induction outcome
Complete remission	39	75.0	40	69.0	79	71.8
Induction failures	13	25.0	18	31.0	31	28.2	1.35a	0.58–3.12	0.48#
Death	3	5.8	11	18.9	14	12.8	3.57a	0.92–13.80	0.05#
Abandonment	7	13.5	3	5.2	10	9.0	0.42a	0.10–1.73	0.32##
Resistant disease	3	5.8	4	6.9	7	6.4	1.3a	0.27–6.19	1.00##
Fever > 38.5°C
Never	35	67.3	29	50.0	64	58.2
Ever	17	32.7	29	50.0	46	41.8	2.06b	0.95–4.47	0.07#
Clinical sepsis
Never	32	61.5	29	50.0	61	55.5
Ever	20	38.5	29	50.0	49	44.5	1.60b	0.75–3.42	0.22#

Notes:

^aORs for any induction failure and specific induction failures (CR is taken as the reference outcome category);

^bORs for event of fever and clinical sepsis (Never is taken as the reference outcome category);

^#Chi-square test;

^##Fisher’s exact test.

Abbreviations: OR, odds ratio (ciprofloxacin group relative to placebo group); CI, confidence interval.