Figure 5. Bone marrow derived FLAP regulate neointima formation.
Four groups of bone marrow transplanted mice were used in wire injury experiments: WT→WT (n=7), FLAP KO→ FLAP KO (n=5), WT→ FLAP KO (n=13) and FLAP KO→WT mice (n=9). Quantification of intima, media, intima/media ratio, stenosis percent were performed in arteries harvested 28 days after wire injury. *P<0.05 **P<0.01,***P<0.001. I/M ratio: intima/media ratio.