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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Pain Med. 2012 Apr;13(Suppl 2):S27–S36. doi: 10.1111/j.1526-4637.2011.01311.x

Figure 3.

Figure 3

Effects of formalin injection in the dorsal hindpaw on escape durations for animals of different ages. Accumulated escape durations for the first 3 responses of each trial are shown. These values were averaged across 5 post-injection weeks for each temperature and age group. Formalin injections significantly increased sensitivity to nociceptive thermal stimulation at 16 and 24 months but not at 8 months. The three age groups along with temperatures tested are shown at the bottom of the figure. All data post-formalin were compared to data obtained pre-formalin (baseline). (Published with permission from Oxford University Press).