Fig. 1.

Measurements of carnitine and acylcarnitine levels in serum and whole blood. Levels of total and free carnitine along with acylcarnitines (esterified carnitine) were measured in serum from the patient (a–d) at various time points during the last decade. Concomitant measurements in serum and whole blood (blood spots on Guthrie cards) drawn from the patient at similar time points were further compared, for their concentration of free carnitine (e) and individual long-chain acylcarnitines (f). Samples from a healthy control were run concomitantly. C0 fatty acyl carbon chain indicates the absence of esterification of carnitine and thus refers to free carnitine