Table 3.

Spearman Rank correlations (ρ) between ammonia and amino acids and between amino acids themselves in all patients and in patients with OTC deficiency, based on age groups (* = p< 0.004)

			All patients (CPS, OTC, ASS deficiency)			OTC deficiency
			All ages	<6 years	6–18 years	All ages	<6 years	6–18 years
Ammonia	GLN	ρ	0.33	0.5	0.08	0.27	0.53	−0.17
		p	*	*	0.64	0.01	*	0.37
Ammonia	PHE:TYR	ρ	−0.24	−0.3	−0.18	−0.4	−0.48	−0.25
		p	0.01	0.02	0.29	*	*	0.19
GLN	GLU	ρ	0	0.26	−0.4	−0.08	0.19	−0.47
		p	0.97	0.04	0.02	0.46	0.17	0.01
GLN	PHE:TYR	ρ	−0.34	−0.45	0	−0.43	−0.49	−0.1
		p	*	*	0.98	*	*	0.61
BCAA#	PHE	ρ	0.47	0.47	0.41	0.6	0.49	0.62
		p	*	*	0.01	*	*	*
BCAA#	TYR	ρ	0.59	0.5	0.59	0.75	0.68	0.71
		p	*	*	*	*	*	*
BCAA#	THR	ρ	0.53	0.44	0.57	0.7	0.57	0.77
		p	*	*	*	*	*	*
BCAA#	LYS	ρ	0.52	0.49	0.40	0.57	0.54	0.41
		p	*	*	0.01	*	*	0.03
BCAA#	HIS	ρ	0.24	0.33	0.13	0.43	0.39	0.36
		p	0.01	0.01	0.47	*	0.01	0.05
BCAA#	MET	ρ	0.32	0.48	0.03	0.47	0.49	0.23
		p	*	*	0.86	*	*	0.22
ALA	GLN	ρ	0.33	0.39	0.18	0.32	0.38	0.14
		p	*	*	0.30	0.05	0.07	0.46
ALA	PRO	ρ	0.6	0.54	0.74	0.65	0.59	0.85
		p	*	*	*	*	*	*
ALA	Ammonia	ρ	0.11	0.02	0.32	0.11	0.05	0.27
		p	0.27	0.87	0.05	0.31	0.74	0.15

#BCAA = Molar sum of LEU, ILE, VAL