Fig. 3.

Alignment of the GC amino acid sequences of several organisms. (a) Human (Gene ID 2629); (b) chimpanzee (Gene ID 449571); (c) orangutan (Gene ID 100174563); (d) rat (Gene ID 684536); (e) mouse (Gene ID 14466); (f) dog (Gene ID 612206); (g) pig (Gene ID 449572); (h) ox (Gene ID 537087); (i) horse (Gene ID 100063514); (j) tick (Gene ID 8051161); (k) C. elegans (Gene ID 178535); (l) honeybee (Gene ID 409708). The boxes indicate conserved residues altered in novel missense mutations. The designation of each mutation is given above the appropriate box