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Proline/citrulline ratio and proline concentration in the neonatal dried blood spot of two affected patients with OAT deficiency (case 1 and case 3). Pro proline, Cit citrulline. The dashed line indicates the 99 percentile of control samples (83.6) obtained from the same sampling day as case 1. Diamond indicates the individual control samples. The solid line indicates the 99 percentile (97.6) of >450,000 blood spot samples analyzed as part of Minnesota NBS program
