Table 1.
symbol | description |
---|---|
N | population size (fixed) |
r | relative fitness of the mutated cell type |
t | time step, N time steps are one generation |
j,k | number of mutants |
Tj→k | probability to go from j to k in one time step |
Mj→kt | probability to go from j to k in t time steps |
ct | number of mutants at time t conditioned upon no extinction, starting from 1 |
〈ct〉 | expected number of mutants at time t conditioned upon no extinction, starting from 1 |
〈ct2〉 | expected of the square of ct |