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Predicted changes in the mean BrdU content (MBC) of the heterogeneous model. Using the parameters estimated for three monkeys in figure 3 we compute the MBC of all cells (dashed line) and of BrdU+ cells (solid line). The experimentally observed BrdU MFI in these monkeys should correlate with the predicted MBC. The MBC of labelled cells hardly declines during the de-labelling phase, which is in agreement with data [13].
