Table 1.

Average parameter values (mean ± s.e.m.) in the models that allow DN1 cells to commit only after a certain number of divisions. The mean values are obtained by averaging solutions for different G sharing a low Akaike index within the same model for commitment of DN1 cells.

description	parameter	unit	geometric	only last generation
probability to commit for DN2 cells	cDN2	dimensionless	0.60 ± 0.02	0.58 ± 0.02
probability to commit for DN3 cells	cDN3	dimensionless	0.284 ± 0.009	0.216 ± 0.002
probability to commit for pDP cells	ccDP	dimensionless	0.466 ± 0.002	0.480 ± 0.004
probability to die for DN1 cells	dDN1	dimensionless	0.13 ± 0.02	0.14 ± 0.02
probability to die for DN2 cells	dDN2	dimensionless	0.033 ± 0.010	0.028 ± 0.007
probability to die for DN3 cells	dDN3	dimensionless	0.227 ± 0.009	0.216 ± 0.002
probability to die for pDP cells	ddDP	dimensionless	0.089 ± 0.005	0.073 ± 0.004
cycle time for DN1 cells	TDN1	day	1.07 ± 0.07	1.10 ± 0.09
cycle time for DN2 cells	TDN2	day	0.685 ± 0.018	0.631 ± 0.023
cycle time for DN3 cells	TDN3	day	2.73 ± 0.20	2.65 ± 0.07
cycle time for pDP cells	TpDP	day	0.581 ± 0.007	0.514 ± 0.014
mean transit time for DN1pre cells	MTTDN1pre	day	2.50 ± 0.13	2.26 ± 0.11
mean transit time for DN1 cells	MTTDN1	day	9.76 ± 0.04	9.69 ± 0.09
mean transit time for DN2 cells	MTTDN2	day	2.47 ± 0.06	2.75 ± 0.09
mean transit time for DN3 cells	MTTDN3	day	1.68 ± 0.09	1.69 ± 0.12
mean transit time for pDP cells	MTTpDP	day	0.599 ± 0.010	0.597 ± 0.021
number of cells entering DN1pre as a bolus	n	cell	194 ± 13	183 ± 17
time of exit from DN1pre	τ	day	2.51 ± 0.13	2.27 ± 0.11
number of DN1pre cells in steady state	NDN1pre	cell	1.25× 102 ± 6.60 × 100	1.13 × 102 ± 5.69 ×100
number of DN1 cells in steady state	NDN1	cell	2.99 × 104 ± 1.54 × 103	2.73 × 104 ± 2.00 × 103
number of DN2 cells in steady state	NDN2	cell	2.75 × 104 ± 1.35 × 103	2.88 × 104 ± 3.23 × 103
number of DN3 cells in steady state	NDN3	cell	3.24 × 106 ± 2.94 × 105	2.63 × 106 ± 5.88 × 105
number of pDP cells in steady state	NpDP	cell	1.87 × 106 ± 3.42 × 105	1.57 × 106 ± 3.63 × 105