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(A) Looping time as a function of DNA circular length for surface tethered DNA (black squares) and vesicle encapsulated DNA molecules (red squares). (B) Looping time for 7 DNA sequences with 63 basepair duplex length and 10 nt overhang. R73 is the standard sequence used in A. Poly-A constructs were constructed by inserting n=10, 17, 26 and 38 consecutive A bases in the middle of a random sequence (E8). Data are means ± SEM (N≥3).
