Table 1.
Treatment | Dose, (mg/kg,p.o.) | Time of onset of diarrhea(min.) | Total number of faeces in 4 h(frequency of defecation in 4 h) | % Inhibition of defecation | Weight of stool(g) |
---|---|---|---|---|---|
Group I |
|
91 ± 10.9 |
8.2 ± 1.5 |
- |
0.72 ± 0.07 |
Group II |
3 |
237.8 ± 2.0b |
1 ± 0.3b |
87.80 |
0.04 ± 0.05b |
Group III |
100 |
145.2 ± 15.3a |
4.8 ± 0.9a |
41.46 |
0.30 ± 0.08b |
Group IV |
200 |
193 ± 14.5b |
3.2 ± 0.2c |
60.98 |
0.20 ± 0.05b |
Group IV | 400 | 212.4 ± 11.3b | 1.4 ± 0.2b | 82.93 | 0.01 ± 0.04b |
Significantly different when compared with that of the control at aP < 0.05, bP < 0.001, cP < 0.01, results are mean ± SEM.