Table 1.
Nine human retrogenes that gained introns investigated in this study
| Retrogene | Parent | Movement | Intron (+) | Intron (−) | Evidence | |
|---|---|---|---|---|---|---|
| TMEM14D |
TMEM14B |
10 < −6 |
1 |
4 |
A |
|
| RPS3AP5 |
RPS3A |
10 < −4 |
1 |
5 |
B |
|
| XXyac-R12DG2.2 |
RCN1 |
13 < −11 |
2* |
5 |
B |
|
| HSP90B2P |
HSP90B1 |
15 < −12 |
2 |
16 |
B |
|
| HSP90AA4P |
HSP90AA1 |
4 < −14 |
3 |
9 |
A,B |
|
| HSP90AA5P |
HSP90AA1 |
3 < −14 |
2 |
7 |
B |
|
| CSMD3 |
RPL18 |
8 < −19 |
1 |
5 |
B |
|
| WBP2NL |
SLC25A5 |
22 < −X |
1 |
3 |
B |
|
| AC019016.1 | CSNK1A1 | 15 < −5 | 2* | 8 | B |
In the column ‘Movement’, ‘10 < −6’ means a new gene on chromosome 10 is retroposed from a gene on chromosome 6, for example. ‘Intron (−)’ and ‘Intron (+)’ are the numbers of intron losses and intron gains in retrocopies, respectively. For ‘Evidence’, ‘A’, confirmed by RT-PCR; ‘B’, supported by convincing transcription evidence. ‘*’ means that the newly evolved intronic regions of XXyac-R12DG2.2 and AC019016.1 could be spliced in two patterns, respectively.